From lab to clinic
نویسندگان
چکیده
منابع مشابه
Kinematics and kinetics of gait: from lab to clinic.
Dynamic gait evaluation allows examination of the intrinsic and extrinsic factors affecting an individual's ability to walk or run. This article identifies the gait cycle so that common terminology can be used to discuss and compare walking and running. The range of motion, or kinematics, used during gait can be seen subjectively in the hallway of the clinic but can be further objectified in a ...
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Dentistry is entering an exciting era in which many of the advances in biotechnology offer opportunities for exploitation in novel and more effective therapies. Pulp healing is complex and dependent on the extent of injury, among many other factors. Many of the molecular and cellular processes involved in these healing events recapitulate developmental processes. The regulation of odontoblast a...
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1,25-Dihydroxyvitamin D (calcitriol), the most active metabolite of vitamin D, has significant antineoplastic activity in preclinical models. Several mechanisms of activity have been proposed. These include inhibition of proliferation associated with cell cycle arrest and, in some models, differentiation, reduction in invasiveness and angiogenesis, and induction of apoptosis. Proposed mechanism...
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Food cue reactivity is a strong motivation to eat, even in the absence of hunger. Therefore, food cue reactivity might sabotage healthy eating, induce weight gain and impede weight loss or weight maintenance. Food cue reactivity can be learned via Pavlovian appetitive conditioning: It is easily acquired but the extinction of appetitive responding seems to be more challenging. Several properties...
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Several experimental therapeutics have been demonstrated to be safe and effective in animal models of neurological disorders, but have failed when they reached the clinic. Postulated factors that affected the poor clinical outcomes include the lack of proper treatment controls and clinically relevant animal models. This failure of lab-to-clinic translation has plagued many neuroprotective drugs...
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ژورنال
عنوان ژورنال: Physics Today
سال: 2017
ISSN: 0031-9228,1945-0699
DOI: 10.1063/pt.3.3639